Anti-Aging Therapies: Can Coffee Protect Against Alzheimer's?

Every coffeehound knows how important thatdisease.
beautiful brew can be. It wakes us up in theCaffeine shown to reverse Alzheimer's symptoms
morning, it's the midafternoon pause thatA recent University of Florida study even
refreshes, and it's the ideal accompaniment tosuggests that caffeine could actually reverse
after-dinner everything, from dessert tosome of the symptoms of Alzheimer's. The study
discussions. We know it makes us feel better ...used mice bred to develop symptoms of the
but can it actually help our brains function better?disease, which were tested to confirm that they
It looks like the answer is yes. A University ofwere exhibiting the same kind of memory
North Carolina study on the effects of drinkingimpairment that human Alzheimer's sufferers
coffee concluded that caffeine is a safe andexperience.
reliable drug that could potentially play a role in theHalf the mice were then put on a daily regimen
therapies against neurological disorders. It is eventhat included the caffeine equivalent of five cups
believed that drinking coffee could help preventcoffee added to their drinking water, while half
Alzheimer's disease, one of the most wide-spreadthe mice had no caffeine added to their water.
and devastating of all age-related disorders.After two months both groups of mice were
How coffee protects the brainretested, and it was found that the mice that had
Coffee's protective powers center on whatbeen drinking the caffeine-added water performed
medical experts call the "blood brain barrier", asignificantly better on memory and thinking skills,
natural filter that guards the central nervousactually testing as well as mice that had not been
system against potentially dangerous chemicalsbred to develop dementia. The mice that had
that may be carried through the rest of thebeen drinking non-caffeinated water showed no
bloodstream. It is believed that high cholesterolimprovement in the tests.
levels in the blood have an adverse effect of thisEven more encouragingly, it was found that the
filter, weakening the barrier against thesebrains of the mice given caffeine showed as
chemicals and leaving the brain vulnerable tomuch as 50% reduction in levels of beta amyloid
damage.protein, which is the basis of the destructive
The University of North Dakota study showedplaque that builds up in the brains of dementia
that after three months of a high-cholesterol diet,patients. The research suggested that caffeine
the blood brain barrier in rabbits that had ingestedhad this effect because it suppresses brain
the equivalent of just one cup of coffee per dayinflammation that leads to over-production of the
was far more intact than the barrier in those thatprotein.
had been given no caffeine.Experts warn that while these results are
Research on Alzheimer's disease indicates that aextremely positive, more research is needed to
weak or "leaky" blood brain barrier that makesdetermine whether caffeine has the same effects
cholesterol damage to the brain possible is amongon people.
the factors that can trigger or contribute to the